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Saturday, March 27, 2010

UK: 3 PhD Scholarships in Digital Translational Genomics at The University of Sheffield

Overview

Healthcare across the Disciplines aims to bring together researchers from non-medical backgrounds to work in partnership with medical professionals and researchers to develop solutions that will impact on patient care, lifelong health and wellbeing. As part of this research theme, three prestigious, University-funded, PhD scholarships are available to start October 2010 as part of an integrated network titled Digital Translational Genomics in Cardiovascular Disease.

Cardiovascular disease is the commonest cause of death worldwide. Recent advances in DNA sequencing (so-called "next-generation sequencing") allow generation of massive amounts of genetic data on patient samples. The NIHR Cardiovascular Biomedical Research Unit (CVBRU) established in 2008 is pioneering the use of this novel technique, coupled with other established techniques (such as microarrays) to characterise gene expression, microRNA expression, and genomic characteristics in patients with a range of cardiovascular disorders. This work ultimately aims to discover novel biomarkers for diagnosis and prognosis, and identification of novel drug targets.

We are seeking three exceptional and highly motivated PhD students to join a network of supervisors from backgrounds in clinical cardiology, genetics, mathematics, engineering, statistics, computing, and bioinformatics. Each project will be jointly supervised and be part of a vibrant network, facilitating an integrated, multidisciplinary approach. We welcome applications from graduates in a numerate discipline who are interested in pursuing multidisciplinary research. Prior experience in the biological sciences is not essential but students must have a willingness to acquire a good grounding in biomedical science and genetics.

Award details

The scholarships cover the cost of Home/EU tuition fees and provides an annual, tax-free maintenance stipend of £13,650. The recipient will also receive a Research Training Support Grant of £1,000. An enhanced stipend may be available for exceptional applicants.


Projects

The proposed PhD projects are:

Project 1: microRNA activity in Acute Coronary Syndromes: discovery of novel functional miRs and potential new drug targets
Project 2: Identification of transcriptional biomarkers for Acute Coronary Syndromes
Project 3: Prediction of genomic regulatory interactions and histone modifications in Acute Coronary Syndromes, using ChIP-Seq assays
The network supervisors are;

Dr Tim Chico (Cardiovascular Science) 0114 2222396/5 t.j.chico@sheffield.ac.uk
Dr Kostas Triantafyllopoulos (Mathematics and Statistics) 0114 2223741 0114 2223741, K.Triantafyllopoulos@sheffield.ac.uk
Dr Marta Milo (Cardiovascular Science) 0114 222386 0114 222386, m.milo@sheffield.ac.uk
Dr Chris Newman (Cardiovascular Science) 0114 271 3194 0114 271 3194, C.Newman@sheffield.ac.uk
Dr Daniel Coca (Automatic Control & Systems Engineering) 0114 222386 0114 222386, d.coca@sheffield.ac.uk
Dr Kevin Walters (Mathematics and Statistics) 0114 222 3720 0114 222 3720, K.Walters@sheffield.ac.uk

Applicants are advised to contact any of the above to discuss their application in the first instance.

Eligible Candidates

- Academic requirements – applicants should have, or expect to achieve, a first or upper second class UK honours degree or equivalent qualifications gained outside the UK in an appropriate area of study.
- Allowed study options – applicants should be registering on their first year of study with the University for 2010/11.
- Residency restrictions – awards are open to UK, EU and international applicants.

How to apply

Applicants are advised to contact the lead supervisor to discuss their application in the first instance.

Complete an application for admission as a postgraduate student. Details of how to apply for admission can be found by following the link on the left. Applications for admission should be submitted as soon as possible.

Wait until you have received an admissions or applicant number.

Download the 'Healthcare across the Disciplines Application Form' from the download box on the right. Read the notes of guidance carefully and send the completed form, together with your CV, two academic references and degree transcripts (if appropriate) to pgr-scholarships@sheffield.ac.uk

The closing date for applications is 21st April 2010 at 5pm.


Please kindly mention Scholarization.blogspot.com when applying for this scholarship


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Scholarship Team: Ph.D Scholar Krisstofferson Joniel Scholarship Adviser, PhD Scholar Chea Vitom Scholarship Adviser and Senior Lecturer, PhD Scholar Rebecca T. Dalisay Scholarship Adviser, Ph.D Student Jiao Wang Scholarship Coordinator, MSc Student Dennise Maricel Scholarship Coordinator