Overview
There is increasing interest in replacing synthetic colourants with natural colourants for foods. Anthocyanins made by plants potentially offer a broad range of colours (orange through red, purple and blue) which have the added advantage of health-promoting properties when incorporated in foods. However the stability of anthocyanins is a problem associated with their application as colourants. Anthocyanins are most stable at low pH, but there their colour range is restricted to red. We have shown that mixing of red/purple anthocyanins with flavonols either in vitro or in vivo results in increased colour intensity, stability and bluing to give indigo colour through a phenomenon known as intermolecular co-pigmentation.
This project will explore the chemical specificity underpinning the development of bluer more stable colours through co-pigmentation using chemical analysis and metabolic engineering techniques. The properties of co-pigmented anthocyanin solutions will be assessed for applications as food colourants, in liquids such as beverages and in solids such as gels and pastes. The effects of processing on colour and its shelf life will be determined using techniques specific for food technology. We will also test the effects of high flavonols, high anthocyanins and high flavonols plus high anthocyanins in extracts of tomato on suppression of the inflammatory response in animal models of inflammatory bowel disease to determine whether these dietary bioactives can reduce the causative effects of this family of chronic diseases.
Studentship benefits
This is a BBSRC funded studentship with full funding to UK Nationals and EU Nationals who have resided in the UK (in full-time education or full-time residency) for 3 years prior to the start date of the studentship. In most other cases EU Nationals will receive funding to cover their tuition-fees only. The stipend for 2010/11 will be £ 13,600 per annum
How to Apply
Please visit the 'How to apply' page of our website for further information and an application pack: http://www.jic.ac.uk/STUDENTS/admissions.htm If you have any further questions please email: graduates.nrp@bbsrc.ac.uk
Application Deadline: 12 noon, 7th December 2009. It is anticipated that interviews will take place in early January. Please note, any successful applicants will be interviewed as part of a studentship competition
For more information and an application pack please visit: http://www.jic.ac.uk/STUDENTS/index.htm
Or email: graduates.nrp@bbsrc.ac.uk
Please kindly mention Scholarization.blogspot.com when applying for this studentship
There is increasing interest in replacing synthetic colourants with natural colourants for foods. Anthocyanins made by plants potentially offer a broad range of colours (orange through red, purple and blue) which have the added advantage of health-promoting properties when incorporated in foods. However the stability of anthocyanins is a problem associated with their application as colourants. Anthocyanins are most stable at low pH, but there their colour range is restricted to red. We have shown that mixing of red/purple anthocyanins with flavonols either in vitro or in vivo results in increased colour intensity, stability and bluing to give indigo colour through a phenomenon known as intermolecular co-pigmentation.
This project will explore the chemical specificity underpinning the development of bluer more stable colours through co-pigmentation using chemical analysis and metabolic engineering techniques. The properties of co-pigmented anthocyanin solutions will be assessed for applications as food colourants, in liquids such as beverages and in solids such as gels and pastes. The effects of processing on colour and its shelf life will be determined using techniques specific for food technology. We will also test the effects of high flavonols, high anthocyanins and high flavonols plus high anthocyanins in extracts of tomato on suppression of the inflammatory response in animal models of inflammatory bowel disease to determine whether these dietary bioactives can reduce the causative effects of this family of chronic diseases.
Studentship benefits
This is a BBSRC funded studentship with full funding to UK Nationals and EU Nationals who have resided in the UK (in full-time education or full-time residency) for 3 years prior to the start date of the studentship. In most other cases EU Nationals will receive funding to cover their tuition-fees only. The stipend for 2010/11 will be £ 13,600 per annum
How to Apply
Please visit the 'How to apply' page of our website for further information and an application pack: http://www.jic.ac.uk/STUDENTS/admissions.htm If you have any further questions please email: graduates.nrp@bbsrc.ac.uk
Application Deadline: 12 noon, 7th December 2009. It is anticipated that interviews will take place in early January. Please note, any successful applicants will be interviewed as part of a studentship competition
For more information and an application pack please visit: http://www.jic.ac.uk/STUDENTS/index.htm
Or email: graduates.nrp@bbsrc.ac.uk
Please kindly mention Scholarization.blogspot.com when applying for this studentship
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