Overview
Due to their sessile life-style, plants are directly exposed to abiotic stresses, including those causing DNA damage. To survive unfavourable conditions, plants have evolved a complex DNA damage surveillance and repair machinery to control and maintain genome integrity. Loss of this control frequently leads to chromosomal aberrations, reduced fitness and, in extreme cases, lethality. Sources of DNA damage (e.g. free radicals, UV light) are unequally distributed in nature. Thus, wild populations exposed to enhanced rates of DNA damage have very likely evolved compensatory mechanisms leading to more effective DNA protection and/or repair. The proposed PhD project will focus on discovery and characterization of variability in DNA damage repair among natural populations of the model plant Arabidopsis thaliana. To this end, genetic, molecular, bioinformatic and biochemical tools will be employed. The results will allow an understanding of the mechanisms of DNA repair and genomic adaptations to local environmental conditions.
Eligible Candidates
The applicant should be highly motivated and possess an MSc or equivalent in Life Sciences. Previous experience in genetic mapping, molecular biology or DNA repair is an advantage.
Application
Please submit your application including a CV and contact details for two referees till August 1st, 2010, to: pecinka@mpipz.mpg.de.
The Max Planck Society is committed to employing more handicapped individuals and especially encourages them to apply. The Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply.
Contact
Dr. Ales Pecinka
E-mail: pecinka@mpipz.mpg.de
Please kindly mention Scholarization.blogspot.com when applying for this opportunity
Due to their sessile life-style, plants are directly exposed to abiotic stresses, including those causing DNA damage. To survive unfavourable conditions, plants have evolved a complex DNA damage surveillance and repair machinery to control and maintain genome integrity. Loss of this control frequently leads to chromosomal aberrations, reduced fitness and, in extreme cases, lethality. Sources of DNA damage (e.g. free radicals, UV light) are unequally distributed in nature. Thus, wild populations exposed to enhanced rates of DNA damage have very likely evolved compensatory mechanisms leading to more effective DNA protection and/or repair. The proposed PhD project will focus on discovery and characterization of variability in DNA damage repair among natural populations of the model plant Arabidopsis thaliana. To this end, genetic, molecular, bioinformatic and biochemical tools will be employed. The results will allow an understanding of the mechanisms of DNA repair and genomic adaptations to local environmental conditions.
Eligible Candidates
The applicant should be highly motivated and possess an MSc or equivalent in Life Sciences. Previous experience in genetic mapping, molecular biology or DNA repair is an advantage.
Application
Please submit your application including a CV and contact details for two referees till August 1st, 2010, to: pecinka@mpipz.mpg.de.
The Max Planck Society is committed to employing more handicapped individuals and especially encourages them to apply. The Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply.
Contact
Dr. Ales Pecinka
E-mail: pecinka@mpipz.mpg.de
Please kindly mention Scholarization.blogspot.com when applying for this opportunity
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