Overview
Department of Parasitology – Unit of Molecular Parasitology
Research context:
The unit of Molecular Parasitology researches treatment failure in leishmaniasis and mechanisms of drug resistance in the causative unicellular parasite Leishmania in a clinical and epidemiological context. New research initiatives were launched which aim to implement state-of-the-art metabolomics and genomic technologies to address research questions in leishmaniasis and the field of infectious diseases in general. These research initiatives are embedded in a high-profile international consortium.
Assignment:
- You will be in charge of implementing a metabolomics platform to characterise the metabolome of Leishmania and whole metabolome variations in Leishmania populations.
- Your daily tasks will consist of 3 activities:
- culturing and preparing Leishmania cultures for mass-spectrometry analysis;
- close interaction with a professional mass-spec team to collect metabolome data on the Leishmania metabolome extracts that you provide;
- processing raw mass-spec metabolome data for comparative biological interpretation, contextualisation and visualisation of global metabolome data which you will also carry out in close interaction with the Strathclyde University (Glasgow) and the systems biology group of the University of Glasgow.
- You will closely interact and collaborate with a team that studies the diversity on whole genome level in Leishmania populations.
- Together with the Sanger genome team and ITM Leishmania team, you will examine genome-metabolome associations and their clinical-biological significance.
- You will explore how metabolomics studies can optimally contribute to advance our understanding of clinical polymorphism in leishmaniasis or other infectious diseases.
Profile:
- You have a PhD in Sciences (e.g. biochemistry/systems biology/ cell metabolomics/pharmaceutical sciences).
- You have an excellent background and demonstrated experience in cell biology and global metabolism.
- You are skilled in cell culturing and manipulation of live pathogens.
- You have programming experience and an ability to use the complex software underlying the automatic data-processing pipeline. Experience with the software environment R for statistical computing is an asset.
- Additional training or background in interpreting and handling chromatographic data and the time/mass/intensity output of the mass spectrometer is an asset.
- You have excellent communication and writing skills in English; you can swiftly integrate in international laboratories and can clearly communicate scientific results to co-workers and other scientists from different disciplines.
Research Field
Biological sciences
- Other
Benefits
We offer:
- A key position in an international multidisciplinary research initiative, pursuing the implementation of genomic, metabolomic and other -omic technologies in research for infectious diseases.
- A full-time position for 3 years. Start date: from September 2010.
- A salary set according to the pay scales of the ITM and the Flemish universities depending on relevant experience and level of education.
- Reimbursement of public transport costs, bicycle compensation, private pension scheme (after two years) and luncheon vouchers.
Interested?
For more information on this vacancy and research context, please contact Prof. Dr. J-C. Dujardin ( +32.3.247.63.58 or jcdujardin@itg.be).
Please use the application form available as a download on www.itg.be/vacatures.
Send the application form, together with your curriculum vitae and letter of motivation, before 10/07/2010, to vacatures@itg.be.
Institute of Tropical Medicine
Department of Parasitology – Unit of Molecular Parasitology
Nationalestraat 155
2000 - Antwerp
Antwerp - BELGIUM
phone +32 3 247 07 05
email vacatures@itg.be
www.itg.be/vacatures
Please kindly mention Scholarization.blogspot.com when applying for this position
Department of Parasitology – Unit of Molecular Parasitology
Research context:
The unit of Molecular Parasitology researches treatment failure in leishmaniasis and mechanisms of drug resistance in the causative unicellular parasite Leishmania in a clinical and epidemiological context. New research initiatives were launched which aim to implement state-of-the-art metabolomics and genomic technologies to address research questions in leishmaniasis and the field of infectious diseases in general. These research initiatives are embedded in a high-profile international consortium.
Assignment:
- You will be in charge of implementing a metabolomics platform to characterise the metabolome of Leishmania and whole metabolome variations in Leishmania populations.
- Your daily tasks will consist of 3 activities:
- culturing and preparing Leishmania cultures for mass-spectrometry analysis;
- close interaction with a professional mass-spec team to collect metabolome data on the Leishmania metabolome extracts that you provide;
- processing raw mass-spec metabolome data for comparative biological interpretation, contextualisation and visualisation of global metabolome data which you will also carry out in close interaction with the Strathclyde University (Glasgow) and the systems biology group of the University of Glasgow.
- You will closely interact and collaborate with a team that studies the diversity on whole genome level in Leishmania populations.
- Together with the Sanger genome team and ITM Leishmania team, you will examine genome-metabolome associations and their clinical-biological significance.
- You will explore how metabolomics studies can optimally contribute to advance our understanding of clinical polymorphism in leishmaniasis or other infectious diseases.
Profile:
- You have a PhD in Sciences (e.g. biochemistry/systems biology/ cell metabolomics/pharmaceutical sciences).
- You have an excellent background and demonstrated experience in cell biology and global metabolism.
- You are skilled in cell culturing and manipulation of live pathogens.
- You have programming experience and an ability to use the complex software underlying the automatic data-processing pipeline. Experience with the software environment R for statistical computing is an asset.
- Additional training or background in interpreting and handling chromatographic data and the time/mass/intensity output of the mass spectrometer is an asset.
- You have excellent communication and writing skills in English; you can swiftly integrate in international laboratories and can clearly communicate scientific results to co-workers and other scientists from different disciplines.
Research Field
Biological sciences
- Other
Benefits
We offer:
- A key position in an international multidisciplinary research initiative, pursuing the implementation of genomic, metabolomic and other -omic technologies in research for infectious diseases.
- A full-time position for 3 years. Start date: from September 2010.
- A salary set according to the pay scales of the ITM and the Flemish universities depending on relevant experience and level of education.
- Reimbursement of public transport costs, bicycle compensation, private pension scheme (after two years) and luncheon vouchers.
Interested?
For more information on this vacancy and research context, please contact Prof. Dr. J-C. Dujardin ( +32.3.247.63.58 or jcdujardin@itg.be).
Please use the application form available as a download on www.itg.be/vacatures.
Send the application form, together with your curriculum vitae and letter of motivation, before 10/07/2010, to vacatures@itg.be.
Institute of Tropical Medicine
Department of Parasitology – Unit of Molecular Parasitology
Nationalestraat 155
2000 - Antwerp
Antwerp - BELGIUM
phone +32 3 247 07 05
email vacatures@itg.be
www.itg.be/vacatures
Please kindly mention Scholarization.blogspot.com when applying for this position
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