Overview
At the Department of Molecular Biology of the University of Bergen (UiB), a PhD level positions as Marie Curie Early Stage Researcher (ESR) is open for three years, with a planned start date no later than October 1, 2010.
The full-time position involve participation in the EU project Nucleosome 4D, which is a Marie Curie Initial Training Network receiving funding from the European Commission’s 7th Framework Programme. The aim of this European network, which brings together 14 partners from 11 countries, is to provide a structured PhD/young-researcher training program on chromatin biology.
About the “Nucleosome 4D” programme:
Chromatin packages a few meters of DNA into a nucleus measuring a few microns. This tight folding occurs by assembling DNA with histones into so-called nucleosomes, thus ensuring the mechanical stability of our genome. On the flipside, this makes nucleosomes a formidable obstacle to the machines that read, copy or repair its DNA message. One of the fundamental questions in biology is to understand how nucleosome structure is established, maintained and manipulated. This network will carry out multidisciplinary, collaborative research projects focused on deciphering nucleosome structures and functions in space and time (Nucleosome 4D). Together our effort will allow our trainees to take the opportunities and meet the challenges of a career in the life science sector through excellent training, effective communication, great teamwork and concrete project management skills.
Specific Research project in Rein Aasland's group
Histone acetylation plays a crucial role in shaping chromatin for gene expression. Several histone acetyltransferases (HATs) act on chromatin, often in concert with transcripton factors and other components of the transcription machinery. While histone acetylation can directly alter the molecular properties of chromatin, a large group of proteins carry domains (bromodomains) that bind and "read" acetylated histones and use this information to modulate the chromatin structure. One such protein is the HAT p300. With its ability to both "read" and "write" acetylation in chromatin, p300 has properties required to copy and spread acetylation along chromosomes. Professor Rein Aasland's lab has recently found a new clue to how p300 is regulated by intra- and intermolecular interactions. The proposed PhD project aims to elucidate the molecular mechanisms by which p300 is regulated using biochemical and cell biological approaches.
Application details
Applicants should have a Master’s degree or equivalent which entitles them to embark on a PhD project in molecular biology, should be in the first four years (full time equivalent) of their research careers, and should not have obtained a PhD yet at the time of employment.
The fellowship is intended to lead to a Ph.D. degree and qualify the successful applicant for a career in academic research. Applicants holding non-Norwegian degrees will have their diplomas assessed for equivalence with a Norwegian masters.
The research fellow must take part in the University’s approved PhD program leading to the degree within a time limit of three years. They will be expected to do research and to partake actively in researcher training courses organised locally and at other Nucleosome 4D partner institutions. Applicants need to have a good working knowledge of English, since all Nucleosome 4D events, as well as dissemination, will be in English.
Applicants must not be Norwegian citizens, except if they have legally resided and had their main activity in a non–associated third country for at least three of the last four years immediately prior to their employment. Furthermore, applicants must not have resided or performed their main activity in Norway for more than 12 months in the three year period immediately prior to employment. For further information on conditions, see here.
Salary will be in accordance with level 45 (code 1017) on the Norwegian government salary scale, this corresponds to a gross monthly salary of about NOK 29617 (approximate EUR 3700), following meriting regulations and Marie Curie guidelines. A compulsory 2% contribution to the State Pension Fund (Statens Pensjonskasse) will be deducted from gross salary.
The Nucleosome 4D project is required by the EC to recruit at least 40% women researchers. Women are particularly encouraged to apply. State employment shall reflect the multiplicity of the population at large to the highest possible degree. We have therefore adopted a personnel policy objective to ensure that we achieve a balanced age and sex composition and the recruitment of persons of various ethnic backgrounds. Persons of all ethnic backgrounds are therefore encouraged to apply for the position.
The University of Bergen applies the principles of public openness when recruiting staff to scientific positions. Information about the applicant may be made public even though the applicant has requested not to be named in the list of applicants. The applicant will be notified if his/her request is not respected.
The successful applicant will be expected to relocate to the University of Bergen and conform to the regulations that apply to the position.
For further information about the available positions and the Nucleosome 4D project, please contact Prof. Rein Aasland (aasland@mbi.uib.no).
Please apply electronically at Jobbnorge (legge inn link til utlysningen i JobbNorge), and enclose the following documents (in pdf):
1. A curriculum vitae including the following information:
•· Name, place and date of birth, address of residence, sex, and marital status.
•· Nationality (or nationalities) and record of residence (countries and periods of residence in those) for the past 3 years.
•· List of academic degrees obtained. For each degree, provide the title in the original language and in English, the awarding institution and the official date of awarding. Indicate the degree (or all degrees) formally entitling you to embark on a doctorate, and which degree (or degrees) constitutes a doctorate, if applicable.
2. A brief list of topics covered in your studies (e.g. a list of courses and the thesis subject), other relevant knowledge and research skills in relevant research areas.
3. Description of research experience after Master’s degree, with calculation in full- time equivalents
4. A list of publications.
5. A sample of relevant written work (e.g. research paper or masters thesis, preferably in English).
6. Copies of all higher education certificates and diplomas, and transcripts of records for exam records (copies of the original documents must be accompanied by a translation into English, Norwegian, Swedish, Danish, or German if not written in any of these languages).
7. Two references and their contact information.
8. An outline (max. 5 pages) of the proposed PhD research related to the current application.
http://www.uib.no/rg/genreg/nyheter/2010/06/phd-position-open-eu-marie-curie-training-programme-nucleosome-4d
Please kindly mention Scholarization.blogspot.com when applying for this opportunity
At the Department of Molecular Biology of the University of Bergen (UiB), a PhD level positions as Marie Curie Early Stage Researcher (ESR) is open for three years, with a planned start date no later than October 1, 2010.
The full-time position involve participation in the EU project Nucleosome 4D, which is a Marie Curie Initial Training Network receiving funding from the European Commission’s 7th Framework Programme. The aim of this European network, which brings together 14 partners from 11 countries, is to provide a structured PhD/young-researcher training program on chromatin biology.
About the “Nucleosome 4D” programme:
Chromatin packages a few meters of DNA into a nucleus measuring a few microns. This tight folding occurs by assembling DNA with histones into so-called nucleosomes, thus ensuring the mechanical stability of our genome. On the flipside, this makes nucleosomes a formidable obstacle to the machines that read, copy or repair its DNA message. One of the fundamental questions in biology is to understand how nucleosome structure is established, maintained and manipulated. This network will carry out multidisciplinary, collaborative research projects focused on deciphering nucleosome structures and functions in space and time (Nucleosome 4D). Together our effort will allow our trainees to take the opportunities and meet the challenges of a career in the life science sector through excellent training, effective communication, great teamwork and concrete project management skills.
Specific Research project in Rein Aasland's group
Histone acetylation plays a crucial role in shaping chromatin for gene expression. Several histone acetyltransferases (HATs) act on chromatin, often in concert with transcripton factors and other components of the transcription machinery. While histone acetylation can directly alter the molecular properties of chromatin, a large group of proteins carry domains (bromodomains) that bind and "read" acetylated histones and use this information to modulate the chromatin structure. One such protein is the HAT p300. With its ability to both "read" and "write" acetylation in chromatin, p300 has properties required to copy and spread acetylation along chromosomes. Professor Rein Aasland's lab has recently found a new clue to how p300 is regulated by intra- and intermolecular interactions. The proposed PhD project aims to elucidate the molecular mechanisms by which p300 is regulated using biochemical and cell biological approaches.
Application details
Applicants should have a Master’s degree or equivalent which entitles them to embark on a PhD project in molecular biology, should be in the first four years (full time equivalent) of their research careers, and should not have obtained a PhD yet at the time of employment.
The fellowship is intended to lead to a Ph.D. degree and qualify the successful applicant for a career in academic research. Applicants holding non-Norwegian degrees will have their diplomas assessed for equivalence with a Norwegian masters.
The research fellow must take part in the University’s approved PhD program leading to the degree within a time limit of three years. They will be expected to do research and to partake actively in researcher training courses organised locally and at other Nucleosome 4D partner institutions. Applicants need to have a good working knowledge of English, since all Nucleosome 4D events, as well as dissemination, will be in English.
Applicants must not be Norwegian citizens, except if they have legally resided and had their main activity in a non–associated third country for at least three of the last four years immediately prior to their employment. Furthermore, applicants must not have resided or performed their main activity in Norway for more than 12 months in the three year period immediately prior to employment. For further information on conditions, see here.
Salary will be in accordance with level 45 (code 1017) on the Norwegian government salary scale, this corresponds to a gross monthly salary of about NOK 29617 (approximate EUR 3700), following meriting regulations and Marie Curie guidelines. A compulsory 2% contribution to the State Pension Fund (Statens Pensjonskasse) will be deducted from gross salary.
The Nucleosome 4D project is required by the EC to recruit at least 40% women researchers. Women are particularly encouraged to apply. State employment shall reflect the multiplicity of the population at large to the highest possible degree. We have therefore adopted a personnel policy objective to ensure that we achieve a balanced age and sex composition and the recruitment of persons of various ethnic backgrounds. Persons of all ethnic backgrounds are therefore encouraged to apply for the position.
The University of Bergen applies the principles of public openness when recruiting staff to scientific positions. Information about the applicant may be made public even though the applicant has requested not to be named in the list of applicants. The applicant will be notified if his/her request is not respected.
The successful applicant will be expected to relocate to the University of Bergen and conform to the regulations that apply to the position.
For further information about the available positions and the Nucleosome 4D project, please contact Prof. Rein Aasland (aasland@mbi.uib.no).
Please apply electronically at Jobbnorge (legge inn link til utlysningen i JobbNorge), and enclose the following documents (in pdf):
1. A curriculum vitae including the following information:
•· Name, place and date of birth, address of residence, sex, and marital status.
•· Nationality (or nationalities) and record of residence (countries and periods of residence in those) for the past 3 years.
•· List of academic degrees obtained. For each degree, provide the title in the original language and in English, the awarding institution and the official date of awarding. Indicate the degree (or all degrees) formally entitling you to embark on a doctorate, and which degree (or degrees) constitutes a doctorate, if applicable.
2. A brief list of topics covered in your studies (e.g. a list of courses and the thesis subject), other relevant knowledge and research skills in relevant research areas.
3. Description of research experience after Master’s degree, with calculation in full- time equivalents
4. A list of publications.
5. A sample of relevant written work (e.g. research paper or masters thesis, preferably in English).
6. Copies of all higher education certificates and diplomas, and transcripts of records for exam records (copies of the original documents must be accompanied by a translation into English, Norwegian, Swedish, Danish, or German if not written in any of these languages).
7. Two references and their contact information.
8. An outline (max. 5 pages) of the proposed PhD research related to the current application.
http://www.uib.no/rg/genreg/nyheter/2010/06/phd-position-open-eu-marie-curie-training-programme-nucleosome-4d
Please kindly mention Scholarization.blogspot.com when applying for this opportunity
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