Sunday, October 10, 2010

Postdoc Position in Organic Chemistry and Chemical Biology, Denmark


A two-year Postdoc position in organic chemistry and chemical biology under the supervision of Associate Professor Christian A. Olsen is available from 1 November 2010 at the Department of Chemistry, DTU.

Project description

The position is part of a program in the lab called: Gene Regulation with Small Molecule Epigenetic Modulators. The work will be focused on the development of novel, robust synthetic methods for efficient, large-scale total synthesis of the non-ribosomal natural product peptide, azumamide E, as well as simplified readily diversifiable analogs for enzymological investigations. With these results as a foundation, the project will include determination of the three-dimensional solution-phase structures of selected compounds using NMR spectroscopy, and evaluation of their interactions with histone deacetylase (HDAC) enzymes by molecular docking into enzyme active sites. After cycles of design, evaluation, and optimization aimed towards isoform- and class-selective candidates, selected compounds will undergo more rigorous testing in cell-based assays.


The successful candidates should have a Ph.D. degree in organic synthetic chemistry, preferably related to biologically active compounds. Excellent communication skills, an interest in chemistry at the interface with biology and medicine, as well as high-impact publications within the field are expected.

We offer

We offer an interesting and challenging job in an international environment focusing on education, research, public-sector consultancy and innovation, which contribute to enhancing the economy and improving social welfare. We strive for academic excellence, collegial respect and freedom tempered by responsibility. The Technical University of Denmark (DTU) is a leading technical university in northern Europe and benchmarks with the best universities in the world.

Salary and appointment terms

The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union.

The period of employment is 2 years.

Further information

Further questions about the projects should be directed to Christian A. Olsen, phone: (+45) 4525 2105.

You can read more about DTU Chemistry on


We must have your online application by 15 October 2010. Please open the link “apply for this job online” and fill in the application form and attach your application, Curriculum Vitae, list of publications, and at least two letters of recommendation. The application must also include documentation of a completed Ph.D. degree.

Applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, race, religion or ethnic background are encouraged to apply.

Please kindly mention when applying for this scholarship

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snoring solutions on October 12, 2010 at 10:43 PM said...

the information is very useful.thanks for this post.Thanks for your valuable contribution!

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