Overview
Systems Biology PhD Studentship: Information processing in the cell: evolution of cross-talk and pleitropy in signalling networks.
Systems biology is an emerging field that combines mathematical analysis, engineering approaches and cutting-edge biological data generation to better understand biological systems. This system-level understanding ties closely to our ability in developing new medicines and biotechnologies.
Biological systems are inherently complex and are a result of evolution. Understanding these systems requires us to draw on mathematical modelling, systems dynamics analysis and in silico simulations of agent-based model systems. In this project, we will utilise these approaches to understand the consequences and emergence of interactions among cellular networks.
Cells have to process several environmental clues, process the information they convey and take appropriate physiological action. Unlike a designed computer, which can utilise distinct modules for separate tasks, cells have molecular networks that are the result of evolution to achieve such signal processing. To date, we lack a clear understanding how these molecular networks can overcome the problem of cross-talk, or conversely, how they could exploit it through evolution.
To address these questions, we will draw both on abstract network-level models and on dynamical modelling of a specific signalling network from different yeast species (in collaboration with the Haynes lab).
For informal enquiries contact Dr Orkun Soyer at O.S.Soyer@exeter.ac.uk
Application criteria
The successful applicant should have or expect to achieve at least an upper second class Honours degree, or equivalent qualifications, with either a mathematical, physical, or biochemical focus. Experience in systems dynamics and computer programming would be beneficial. Candidates are expected to have a genuine interest in biology/evolution and to be motivated in expanding their skill set and working at the interface of biology and computational/mathematical biology.
Please note that studentships will be awarded on the basis of merit.
Value: Three-year studentship: Tuition fees [UK/EU or International] and an annual maintenance allowance at current research council rate
Application deadline: 14th March 2011
How to apply
To apply, you must complete the online web form. You will be asked to submit some personal details and upload a full CV, covering letter and details of two academic referees. Your covering letter should outline your academic interests, prior research experience and reasons for wishing to undertake this project.
For general enquiries please contact Liz Roberts at E.G.Roberts@exeter.ac.uk
Please quote Scholarization.blogspot.com on your application when applying for this scholarship
Systems Biology PhD Studentship: Information processing in the cell: evolution of cross-talk and pleitropy in signalling networks.
Systems biology is an emerging field that combines mathematical analysis, engineering approaches and cutting-edge biological data generation to better understand biological systems. This system-level understanding ties closely to our ability in developing new medicines and biotechnologies.
Biological systems are inherently complex and are a result of evolution. Understanding these systems requires us to draw on mathematical modelling, systems dynamics analysis and in silico simulations of agent-based model systems. In this project, we will utilise these approaches to understand the consequences and emergence of interactions among cellular networks.
Cells have to process several environmental clues, process the information they convey and take appropriate physiological action. Unlike a designed computer, which can utilise distinct modules for separate tasks, cells have molecular networks that are the result of evolution to achieve such signal processing. To date, we lack a clear understanding how these molecular networks can overcome the problem of cross-talk, or conversely, how they could exploit it through evolution.
To address these questions, we will draw both on abstract network-level models and on dynamical modelling of a specific signalling network from different yeast species (in collaboration with the Haynes lab).
For informal enquiries contact Dr Orkun Soyer at O.S.Soyer@exeter.ac.uk
Application criteria
The successful applicant should have or expect to achieve at least an upper second class Honours degree, or equivalent qualifications, with either a mathematical, physical, or biochemical focus. Experience in systems dynamics and computer programming would be beneficial. Candidates are expected to have a genuine interest in biology/evolution and to be motivated in expanding their skill set and working at the interface of biology and computational/mathematical biology.
Please note that studentships will be awarded on the basis of merit.
Value: Three-year studentship: Tuition fees [UK/EU or International] and an annual maintenance allowance at current research council rate
Application deadline: 14th March 2011
How to apply
To apply, you must complete the online web form. You will be asked to submit some personal details and upload a full CV, covering letter and details of two academic referees. Your covering letter should outline your academic interests, prior research experience and reasons for wishing to undertake this project.
For general enquiries please contact Liz Roberts at E.G.Roberts@exeter.ac.uk
Please quote Scholarization.blogspot.com on your application when applying for this scholarship
0 comments:
Post a Comment