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Friday, August 20, 2010

Postdoc 'Large Scale Distributed Computing for Multiscale Biomedical Applications'

Overview

We offer a two year postdoctoral position in the field of large scale computing for biomedical applications, located in the Computational Science research group of the Faculty of Science of the University of Amsterdam. The position is part of MeDDiCa, a large European research project in the field of medical devices for cardiovascular applications. The aim of the research is to explore large scale distributed computing in the domain of multiscale biomedical simulations, exploiting high-end infrastructures as offered by PRACE and EGI.

MeDDiCA is a Marie Curie Initial Training Network sponsored by the European Commission. This network consists of 16 partners from all over Europe. MeDDiCA (Medical Devices Design in Cardiovascular Applications) investigates, through modelling and simulation, percutaneous stent devices and artificial heart valves. The research is multidisciplinary, ranging from medicine and biology to physics, engineering and computational science. The research at the University of Amsterdam is focussed on multiscale modelling and simulation, as well as large scale distributed multiscale computing. You will be working with three PhD students (supervising one), and another postdoc, forming a team working on multiscale modelling and simulation in the domain of the Virtual Physiological Human (VPH). Being embedded in the seminal well-recognized VPH research the work on MeDDiCA offers opportunities to establish sustainable collaborations with the diverse research groups in this framework.


Tasks

You will investigate and apply large scale distributed computing in the domain of multiscale biomedical simulations, exploiting high-end infrastructures as offered by PRACE and EGI. In previous projects we developed a multiscale model for in-stent restenosis that contains four coupled models for blood flow, smooth muscle cell proliferation, drug diffusion, and thrombus formation as well as a separate simulation to set up initial conditions. Running such coupled models in three dimensions under realistic settings requires the use of high performance computing capabilities. You will research the novel paradigm of Distributed Multiscale Computing, ranging from the theory of multiscale coupling to implementational aspects, and apply it to challenging applications in the biomedical domain, as being worked on in the MeDDiCA project.

The research will focus on:

■Establishing a universal distributed multiscale simulation environment on large scale European e-Infrastructures (PRACE, EGI), in collaboration with the MAPPER project, resulting in a high-quality open source tool for the VPH community and beyond
■A prototypical three dimensional simulation for in-stent restenosis in this environment
■3D simulations of in-stent restenosis investigating new stent designs
■Extend the distributed multiscale simulation environment to other multiscale simulations within the MeDDiCA project

Requirements

Candidates should have a PhD degree in Computational Science, Computer Science, Computational Physics, Biomedical Engineering or related disciplines. Applicants should have a proven track record in large scale computing. Direct experience with Grid computing is not required, but candidates should have a strong affinity with such modes of distributed computing. Experience in the biomedical field is not immediately needed, but a strong interest is required. Candidates should form a bridge between the HPC community and the Biomedical engineering community, and should therefore be capable to ‘speak both languages', and should be willing to publish both in Computational Science journals as well as Biomedical Engineering journals. Candidates should be able to work in an international multidisciplinary team. Moreover, given the nature of the MeDDiCA project, the candidate should be willing to participate in all project related networking activities. As this research is sponsored under the Marie Curie initiative, the Marie Curie mobility rules apply. So, before applying, candidates are requested to check their eligibility. Details can be found on the MeDDiCA website.

Further information

Dr Alfons G. Hoekstra, 020 525 7543, A.G.Hoekstra@uva.nl.
Some background material can be found at the MAPPER and Coast websites (for links see below).

Appointment

The appointment will be on a temporary basis for a maximum period of two years. The gross monthly salary is in accordance with the university regulations for academic personnel, and will range from €2,379 up to a maximum of €3,755 (scale 10). The holiday allowance is 8% of the annual gross income. Furthermore, there will be an annual bonus of 8.3% of the annual gross income. The Collective Employment Agreement of the Dutch Universities applies. There are also secondary allowances that will be paid in accordance with the rules for Marie Curie Initial Training Networks.

Job application

Applications including a detailed curriculum vitae and a motivation letter, marked "strictly confidential" and quoting job reference number 10-1074 in the upper left-hand corner of the envelope, should be sent to: Universiteit van Amsterdam, Faculty of Science - Personnel Dept., attn: C. Knaap-Cabi, Postbus 94216, 1090 GE, Amsterdam, The Netherlands. Applications can also be emailed to application-science@uva.nl. Please quote the job reference number in the subject line.

The closing date is 19 November 2010.


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Scholarship Team: Ph.D Scholar Krisstofferson Joniel Scholarship Adviser, PhD Scholar Vitom Chea Scholarship Adviser, PhD Scholar Rebecca T. Dalisay Scholarship Adviser, Ph.D Student Jiao Wang Scholarship Coordinator, MSc Student Dennise Maricel Scholarship Coordinator
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Scholarship Team: Ph.D Scholar Krisstofferson Joniel Scholarship Adviser, PhD Scholar Chea Vitom Scholarship Adviser and Senior Lecturer, PhD Scholar Rebecca T. Dalisay Scholarship Adviser, Ph.D Student Jiao Wang Scholarship Coordinator, MSc Student Dennise Maricel Scholarship Coordinator