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Tuesday, February 16, 2010

UK: PhD Studentship on the Molecular Cell Biology of Lowe Syndrome, University College London

Overview

Applications are invited for a 3-year PhD studentship funded by the Lowe Syndrome Trust, commencing in October 2010. The studentship covers a tax-free stipend (£16,000 rising by £500 each year, to reach £17,000) in addition to covering tuition fees at the UK/EU rate.

Studentship Description

The project aims to understand the role of the OCRL1 protein in polarised epithelial cells. OCRL1 mutation causes Lowe Syndrome, a genetic disorder affecting the brain, eyes, and kidneys. This project will build on our recent exciting novel findings that OCRL1 is required for normal maturation of tight junctions. Work will include biochemical and cell biological analysis, development of new 3-dimensional tissue culture growth systems, and the use of RNAi screening to find potential drug targets for what is currently an untreatable condition. The successful candidate will therefore gain wide experience that will benefit anyone who wishes to establish a career in biomedical science. We are looking for very motivated candidates with excellent scientific potential.

Stipend: £16,000 rising by £500 each year to reach £17,000

The UCL Institute of Ophthalmology carries out research in well-equipped laboratories adjacent to Moorfields Eye Hospital NHS Trust. The Institute achieved the highest ratings in the last four RAE assessments. Work within the Institute ranges widely, from basic sciences to translational research, and is an ideal environment for research training. The PhD student will benefit from state-of-art facilities both at the UCL Institute of Ophthalmology and in the UCL School of Life and Medical Sciences.


Person Specification

Applicants should hold (or expect to obtain) a minimum upper-second degree or equivalent in molecular cell biology, or an associated subject such as biochemistry, developmental biology, biological sciences, or genetics. Previous laboratory-based research experience is desirable.

Eligibility

Formal applications should be submitted in the form of a CV and covering letter outlining motivation, interest, and suitability for this project to Dr Tim Levine at tim.levine@ucl.ac.uk. Contact details for two references should also be provided.

Contact name: Dr Tim Levine

Contact details: tim.levine@ucl.ac.uk
UCL Taking Action for Equality
Closing Date: 26 Mar 2010
Studentship Start Date: October 2010


Please kindly mention Scholarization.blogspot.com when applying for this studentship


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Scholarship Team: Ph.D Scholar Krisstofferson Joniel Scholarship Adviser, PhD Scholar Chea Vitom Scholarship Adviser and Senior Lecturer, PhD Scholar Rebecca T. Dalisay Scholarship Adviser, Ph.D Student Jiao Wang Scholarship Coordinator, MSc Student Dennise Maricel Scholarship Coordinator