Overview
High-Throughput -Toxicity-Screening by means of in-vitro methods for testing of selected chemicals and nano-particles in mixtures.
Program Description
The primary objective of this ITN is to contribute to the education of environmental chemo-informaticians who will receive an advanced training in both environmental sciences and computational in silico methods.
The fellows of the network are expected to apply their knowledge for the implementation of REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) in particular with respect to the replacement, refinement and reduction of animal tests by alternative (in silico and in vitro) methods.
Research will assess applicability of experimental high throughput screening (HTS) methods for the assessment of toxicity of nano-particles and of a standard Water Framework Directive (WFD) list of compounds (both single and mixtures) using several protocols (Tetrahymena species, rat hepatoma cells (H4IIE), transfected yeasts cells (S. cerevisiae) with the human estrogen receptor (hER α)).
The results of the experiments with WFD-list compounds will be important to compare their toxic effects in the bulk state with those of nano-particles and to better understand their mode of action. This will allow better to understand which factors govern their behaviour and bioavailability as well as the toxicological effects of the chemicals and materials tested.
Research Field
Chemistry - Analytical chemistry
Required qualifications:
- Master / diploma in chemistry, biology, biochemistry, geoecology
- Profound experience in cell culture work
- Some background in analytical chemistry involving ideally GC-MS and isotope dilution techniques
- Strong interest in molecular ecotoxicology, particularly also in in-silico screening techniques
- Interest to work in an interdisciplinary environment involving interactions between chemistry, biology, modelling, and health.
- Highly motivated for the project, like to work with others, integrate into a team
Formal applications should be exclusively send electronically to the following website
http://www.eco-itn.eu/ -> Open Positions -> Short Term - > STR1
and should include:
- Full CV and non German citizenship
- A statement of motivation (not more than one page)
- Copies of relevant exams, grades, master thesis work or publications
- Contact information of two reference persons
- Interest and willingness to stay in Turkey for at least 6 months for field work
This position is funded by EU and the applicants should check their eligibility as indicated at the web site of the project.
Application Deadline
31/12/2010
Helmholtz-Zentrum München
Research Laboratory
- Munich
GERMANY
phone +49 (0)89 3187 3147
email schramm@helmholtz-muenchen.de
http://www.eco-itn.eu/
Please kindly mention Scholarization.blogspot.com when applying for this fellowship
High-Throughput -Toxicity-Screening by means of in-vitro methods for testing of selected chemicals and nano-particles in mixtures.
Program Description
The primary objective of this ITN is to contribute to the education of environmental chemo-informaticians who will receive an advanced training in both environmental sciences and computational in silico methods.
The fellows of the network are expected to apply their knowledge for the implementation of REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) in particular with respect to the replacement, refinement and reduction of animal tests by alternative (in silico and in vitro) methods.
Research will assess applicability of experimental high throughput screening (HTS) methods for the assessment of toxicity of nano-particles and of a standard Water Framework Directive (WFD) list of compounds (both single and mixtures) using several protocols (Tetrahymena species, rat hepatoma cells (H4IIE), transfected yeasts cells (S. cerevisiae) with the human estrogen receptor (hER α)).
The results of the experiments with WFD-list compounds will be important to compare their toxic effects in the bulk state with those of nano-particles and to better understand their mode of action. This will allow better to understand which factors govern their behaviour and bioavailability as well as the toxicological effects of the chemicals and materials tested.
Research Field
Chemistry - Analytical chemistry
Required qualifications:
- Master / diploma in chemistry, biology, biochemistry, geoecology
- Profound experience in cell culture work
- Some background in analytical chemistry involving ideally GC-MS and isotope dilution techniques
- Strong interest in molecular ecotoxicology, particularly also in in-silico screening techniques
- Interest to work in an interdisciplinary environment involving interactions between chemistry, biology, modelling, and health.
- Highly motivated for the project, like to work with others, integrate into a team
Formal applications should be exclusively send electronically to the following website
http://www.eco-itn.eu/ -> Open Positions -> Short Term - > STR1
and should include:
- Full CV and non German citizenship
- A statement of motivation (not more than one page)
- Copies of relevant exams, grades, master thesis work or publications
- Contact information of two reference persons
- Interest and willingness to stay in Turkey for at least 6 months for field work
This position is funded by EU and the applicants should check their eligibility as indicated at the web site of the project.
Application Deadline
31/12/2010
Helmholtz-Zentrum München
Research Laboratory
- Munich
GERMANY
phone +49 (0)89 3187 3147
email schramm@helmholtz-muenchen.de
http://www.eco-itn.eu/
Please kindly mention Scholarization.blogspot.com when applying for this fellowship
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