PhD Studentships For Degree Holders In Biology Related Field At National University Ireland Galway
Title: molecular recognition of glycans in human disease
Studentships Background:
Variations in the carbohydrate sequence of glycans on cell surfaces are markers for several cancers and congenital and acquired diseases, including, pancreatic, breast, and liver cancer, diabetes, IgA nephropathy, Alzheimer’s. The discovery and detection of these glycans is currently hindered by the lack of appropriate reagents. In this project, we are using computational methods to guide re-engineering of carbohydrate-degrading enzymes to convert them into high-affinity receptor proteins suitable for use as glycan biosensors.
The project provides training in protein expression, engineering and biophysical characterization, using such techniques as site-directed and random mutagenesis, surface plasmon resonance and flow cytometry. The PhD student will have the opportunity to participate in the computational design of protein mutants, according to their interests and abilities, and will work closely with a team of computational chemists. No previous experience with protein expression and characterization is required. This project is funded by Science Foundation Ireland under the Principle Investigator Programme with partners at the University of Georgia, USA.
Studentships Requirements:
Candidates should have a degree in chemistry, biochemistry, molecular biology or a closely related discipline, and a strong motivation for research into problems in human health.
Studentships Applications:
(curriculum vitae, academic degree, references) should be sent to Prof. Rob Woods ( rob.woodsnuigalway), National University of Ireland, Galway, School of Chemistry, University Road, Galway, Ireland.
Studentships Stipend & Start Date:
A fixed stipend of €18,000 per year is available. Tuition fees will be covered by the project, and there is a generous travel grant for the attendance at international meetings. It is anticipated that the PhD candidate will commence in September 2009.
Source: www.nuigalway.ie
Please kindly mention Scholarization.blogspot.com when applying for this scholarship
Title: molecular recognition of glycans in human disease
Studentships Background:
Variations in the carbohydrate sequence of glycans on cell surfaces are markers for several cancers and congenital and acquired diseases, including, pancreatic, breast, and liver cancer, diabetes, IgA nephropathy, Alzheimer’s. The discovery and detection of these glycans is currently hindered by the lack of appropriate reagents. In this project, we are using computational methods to guide re-engineering of carbohydrate-degrading enzymes to convert them into high-affinity receptor proteins suitable for use as glycan biosensors.
The project provides training in protein expression, engineering and biophysical characterization, using such techniques as site-directed and random mutagenesis, surface plasmon resonance and flow cytometry. The PhD student will have the opportunity to participate in the computational design of protein mutants, according to their interests and abilities, and will work closely with a team of computational chemists. No previous experience with protein expression and characterization is required. This project is funded by Science Foundation Ireland under the Principle Investigator Programme with partners at the University of Georgia, USA.
Studentships Requirements:
Candidates should have a degree in chemistry, biochemistry, molecular biology or a closely related discipline, and a strong motivation for research into problems in human health.
Studentships Applications:
(curriculum vitae, academic degree, references) should be sent to Prof. Rob Woods ( rob.woodsnuigalway), National University of Ireland, Galway, School of Chemistry, University Road, Galway, Ireland.
Studentships Stipend & Start Date:
A fixed stipend of €18,000 per year is available. Tuition fees will be covered by the project, and there is a generous travel grant for the attendance at international meetings. It is anticipated that the PhD candidate will commence in September 2009.
Source: www.nuigalway.ie
Please kindly mention Scholarization.blogspot.com when applying for this scholarship
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