Tumor Microenvironment Postdoctoral Positions – Burnham Institute For Medical Research, USA 2009

Faculty: NCI-Designated Cancer Center

Postdoctoral Position Description:

This project is based on the idea that toxic secondary bile acids are central to the onset and progression of colorectal cancer. We have made two new observations in the field: i) we identified a variant of the cytoplasmic Ileal bile-acid Binding Protein (IBABP) that is essential for the survival of colon tumor cells (Fang et al., Cancer Research 2007), and is a likely drug target, ii) we have also established that IBABP is necessary for the transcriptional activation of FXR, providing a unique mechanistic insight into the biological connection between bile acids and transcription. Prospective fellows should have direct training in one or more the following areas: tumor biology of colorectal cancer, cell biology of colorectal cancer, bile acid biochemistry and enzymology, synthesis of bile acid analogs, or animal models of colorectal cancer.

Applications For Position:

Candidates with a PhD. Interested applicants should reference, Basic Mechanisms Underlying Colorectal Cancer, and submit a copy of their CV, a brief statement of research skills, and contact information (email address and phone number) of three references to: James Lee (jameslee@burnham.org).

Position Location: La Jolla, CA

Contact Details:
Bile Acids in Colorectal Cancer
Principal Investigator: Jeff Smith
E-Mail: jameslee@burnham.org

Contact Address:
California
Burnham Institute for Medical Research
10901 North Torrey Pines Road
La Jolla, CA 92037
Or
Florida
Burnham Institute for Medical Research at Lake Nona
6400 Sanger Road
Orlando, FL 32827

Website: http://www.burnham.org/

Please kindly mention scholarization.blogspot.com when applying for this scholarship